engleski

Influence of hyperglycaemia on stroke outcome

Introduction Influence of hyperglycaemia on stroke outcome is nown. We wanted to investigate the influence of blood glucose evel on admission on stroke severity and outcome in diabetic DM) and non-diabetic patients (non-DM). Methods Prospective study included 106 patients with ischemic -rroke admitted to intensive care within 6 hours after stroke : nset. In all patients blood glucose level at admission and twice - day during first 72 hours after stroke onset was measured mmol/1). Stroke severity on admission was assessed using Scandinavian stroke scale (SSSa) and outcome in survivors -sing Barthel index (BI). Results Out of 106 patients 28 had diabetes. Mean glucose at -emission was 9.3 mmol/1 in DM and 6.9 mmol/1 in non-DM. -lean SSSa didn't significantly differ between DM and non-DM. DM with glucose at admission >9.1 had significantly ?wer SSSa (mean =17.5) than DM with glucose <9.1 :Tiean=20). Similar was in non-DM group: in patients with ---ucose >9.1 mean SSSa was 20.4 and with glucose <9.1 SSSa as 13.3. During first 24-48 hours in DM group significant ' >e of glucose occurred. DM had worse outcome than non-DM -egardless of glucose on admission. But in non-DM significant -.rYerence in outcome regarding glucose on admission was rresent: in patients with glucose <9.1 mean BI was 38.8 and -ith glucose >9.1 BI was 26.2. Conclusions We found no certain evidences of diabetes melli-'^s influence on stroke severity, but it is evident that it is assorted with slower recovery and poor outcome, especially ifglu- -ose level at admission is higher.

glucose; stroke

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