Do or Die: HPV E5, E6 and E7 in Cell Death Evasion (CROSBI ID 314644)
Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija
Podaci o odgovornosti
Skelin, Josipa ; Sabol, Ivan ; Tomaić, Vjekoslav
engleski
Do or Die: HPV E5, E6 and E7 in Cell Death Evasion
Abstract: Human papillomaviruses (HPVs) infect the dividing cells of human epithelia and hijack the cellular replication machinery to ensure their own propagation. In the effort to adapt the cell to suit their own reproductive needs, the virus changes a number of processes, amongst which is the ability of the cell to undergo programmed cell death. Viral infections, forced cell divisions and mutations, which accumulate as a result of uncontrolled proliferation, all trigger one of several cell death pathways. Here, we examine the mechanisms employed by HPVs to ensure the survival of infected cells manipulated into cell cycle progression and proliferation.
E5 ; E6 ; E7 ; HPV ; cervical cancer ; apoptosis ; autophagy ; anoikis ; pyroptosis
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Podaci o izdanju
Povezanost rada
Biologija, Temeljne medicinske znanosti