engleski

DEVELOPMENT OF NEW COST-EFFECTIVE MICROFLUIDICS METHOD FOR CARNOSINE DETERMINATION IN DIETARY SUPPLEMENTS

Dipeptide L-carnosine is used in dietary supplements formulations to improve endurance during intense exercise. This report describes the new microchip electrophoresis (MCE) method to determine L-carnosine in dietary supplements samples. Capacitively coupled contactless conductivity detection (C4D) was employed as an alternative to expensive, timeconsuming, and complex detection methods commonly used for peptides detection. Detector response showed high linearity in the tested range of 2.5 – 25 µmol/L. The separation was rapid, owing to 73 s migration time of L-carnosine. The proposed microfluidic method showed great potential for further analysis of L-carnosine in dietary supplement samples.

carnosine ; C4D detector ; dietary supplements ; microchip capillary electrophoresi

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