hrvatski

Učinak metode dekontaminacije površine implantata fotodinamičkom terapijom u regenerativnoj kirurgiji periimplantitisa

Implant surface decontamination plays a crucial and important step in peri-implantitis therapy. The primary goal of implant surface decontamination is to eradicate bacteria and their products from dental implant surface and surrounding tissues, ensuring implant survival while simultaneously promoting surrounding peri- implant tissues regeneration. Several implant surface decontamination methods have been proposed to prevent bacterial resistance development or/and surface damage. Photodynamic therapy (PDT) has been proposed as an adjuvant to surgical peri- implantitis therapy. The study aimed to assess clinical, microbiological and immunological outcomes 12 and 24 months after peri-implantitis regenerative surgical procedure, performing two divide implant surface decontamination methods. Materials and methods: In the test group, during the surgical procedure, implant surface decontamination was conducted by means of titanium curettes and PDT, while in a control group, 1 % gel of chlorhexidine (CHX) was used. Clinical parameters including bleeding on probing (BOP), plaque index, peri-implant probing depth (PPD), clinical attachment level ; immunological (IL-17, IL-1β, IL-6) and microbiological parameters, were assessed at 12 and 24 months postoperatively. Results: Both groups showed a statistically significant improvement in clinical outcomes. There was a significant reduction in terms of PPD and BOP in the test group compared to the control one, 12 and 24 months after the surgery (p < 0.05). A statistically significant better result in a reduction of peri-implantitis causatives’ bacteria and pro-inflammatory IL concentrations were achieved by means of PDT in the test group (p < 0.05) compared to CHX application in the control group, 12 and 24 months postoperatively. Conclusion: PDT may be suggested as an effective adjuvant implant surface decontamination method to the surgical regenerative treatment of peri- implantitis, resulting in clinical outcomes enhancement and reduction of pathogenic bacteria and pro- inflammatory interleukins.

periimplantitis ; dijagnoza ; fotodinamska terapija ; regenerativna kirurgija

nije evidentirano

engleski

The effect of implant surface decontamination method by means of photodynamic therapy in periimplantitis regenerative surgery

Implant surface decontamination plays a crucial and important step in peri-implantitis therapy. The primary goal of implant surface decontamination is to eradicate bacteria and their products from dental implant surface and surrounding tissues, ensuring implant survival while simultaneously promoting surrounding peri- implant tissues regeneration. Several implant surface decontamination methods have been proposed to prevent bacterial resistance development or/and surface damage. Photodynamic therapy (PDT) has been proposed as an adjuvant to surgical peri- implantitis therapy. The study aimed to assess clinical, microbiological and immunological outcomes 12 and 24 months after peri-implantitis regenerative surgical procedure, performing two divide implant surface decontamination methods. Materials and methods: In the test group, during the surgical procedure, implant surface decontamination was conducted by means of titanium curettes and PDT, while in a control group, 1 % gel of chlorhexidine (CHX) was used. Clinical parameters including bleeding on probing (BOP), plaque index, peri-implant probing depth (PPD), clinical attachment level ; immunological (IL-17, IL-1β, IL-6) and microbiological parameters, were assessed at 12 and 24 months postoperatively. Results: Both groups showed a statistically significant improvement in clinical outcomes. There was a significant reduction in terms of PPD and BOP in the test group compared to the control one, 12 and 24 months after the surgery (p < 0.05). A statistically significant better result in a reduction of peri-implantitis causatives’ bacteria and pro-inflammatory IL concentrations were achieved by means of PDT in the test group (p < 0.05) compared to CHX application in the control group, 12 and 24 months postoperatively. Conclusion: PDT may be suggested as an effective adjuvant implant surface decontamination method to the surgical regenerative treatment of peri- implantitis, resulting in clinical outcomes enhancement and reduction of pathogenic bacteria and pro- inflammatory interleukins.

peri-implantitis ; implant ; diagnosis ; photodynamic therapy ; regenerative surgery

nije evidentirano