Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1216769

Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia)


Smodlaka Tanković, Mirta; Baričević, Ana; Gerić, Marko; Domijan, Ana-Marija; Marić Pfannkuchen, Daniela; Kužat, Nataša; Ujević, Ivana; Kuralić, Malissa; Rožman, Marko; Matković, Katarina et al.
Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia) // Environmental research, 214 (2022), 114108, 12 doi:10.1016/j.envres.2022.114108 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1216769 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia)

Autori
Smodlaka Tanković, Mirta ; Baričević, Ana ; Gerić, Marko ; Domijan, Ana-Marija ; Marić Pfannkuchen, Daniela ; Kužat, Nataša ; Ujević, Ivana ; Kuralić, Malissa ; Rožman, Marko ; Matković, Katarina ; Novak, Matjaž ; Žegura, Bojana ; Pfannkuchen, Martin ; Gajski, Goran

Izvornik
Environmental research (0013-9351) 214 (2022); 114108, 12

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Pseudo-nitzschia ; Domoic acid ; human peripheral blood cells ; Cyto/genotoxicity ; environmental safety

Sažetak
Diatoms of the genus Pseudo-nitzschia are cosmopolitans spread in seas and oceans worldwide, with more than 50 described species, dozens of which have been confirmed to produce domoic acid (DA). Here, we characterized and investigated the toxicological activity of secondary metabolites excreted into the growth media of different Pseudo-nitzschia species sampled at various locations in the northern Adriatic Sea (Croatia) using human blood cells under in vitro conditions. The results revealed that three investigated species of the genus Pseudo-nitzschia were capable of producing DA indicating their toxic potential. Moreover, toxicological data suggested all three Pseudo-nitzschia species can excrete toxic secondary metabolites into the surrounding media in addition to the intracellular pools of DA, raising concerns regarding their toxicity and environmental impact. In addition, all three Pseudo-nitzchia species triggered oxidative stress, one of the mechanisms of action likely responsible for the DNA damage observed in human blood cells. In line with the above stated, our results are of great interest to environmental toxicologists, the public and policy makers, especially in light of today's climate change, which favours harmful algal blooms and the growth of DA producers with a presumed negative impact on the public health of coastal residents.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Interdisciplinarne prirodne znanosti



POVEZANOST RADA


Projekti:
UIP-2014-09-6563 - Životne strategije fitoplanktona u sjevernom Jadranu (P-limit) (Pfannkuchen, Martin, HRZZ - 2014-09) ( CroRIS)
HRZZ-UIP-2020-02-7868 - Molekularne životne strategije fitoplanktona u Jadranu (Adri LIFE) (Marić Pfannkuchen, Daniela, HRZZ - 2020-02) ( CroRIS)

Ustanove:
Institut za oceanografiju i ribarstvo, Split,
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Prehrambeno-biotehnološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com doi.org

Citiraj ovu publikaciju:

Smodlaka Tanković, Mirta; Baričević, Ana; Gerić, Marko; Domijan, Ana-Marija; Marić Pfannkuchen, Daniela; Kužat, Nataša; Ujević, Ivana; Kuralić, Malissa; Rožman, Marko; Matković, Katarina et al.
Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia) // Environmental research, 214 (2022), 114108, 12 doi:10.1016/j.envres.2022.114108 (međunarodna recenzija, članak, znanstveni)
Smodlaka Tanković, M., Baričević, A., Gerić, M., Domijan, A., Marić Pfannkuchen, D., Kužat, N., Ujević, I., Kuralić, M., Rožman, M. & Matković, K. (2022) Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia). Environmental research, 214, 114108, 12 doi:10.1016/j.envres.2022.114108.
@article{article, author = {Smodlaka Tankovi\'{c}, Mirta and Bari\v{c}evi\'{c}, Ana and Geri\'{c}, Marko and Domijan, Ana-Marija and Mari\'{c} Pfannkuchen, Daniela and Ku\v{z}at, Nata\v{s}a and Ujevi\'{c}, Ivana and Kurali\'{c}, Malissa and Ro\v{z}man, Marko and Matkovi\'{c}, Katarina and Novak, Matja\v{z} and \v{Z}egura, Bojana and Pfannkuchen, Martin and Gajski, Goran}, year = {2022}, pages = {12}, DOI = {10.1016/j.envres.2022.114108}, chapter = {114108}, keywords = {Pseudo-nitzschia, Domoic acid, human peripheral blood cells, Cyto/genotoxicity, environmental safety}, journal = {Environmental research}, doi = {10.1016/j.envres.2022.114108}, volume = {214}, issn = {0013-9351}, title = {Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia)}, keyword = {Pseudo-nitzschia, Domoic acid, human peripheral blood cells, Cyto/genotoxicity, environmental safety}, chapternumber = {114108} }
@article{article, author = {Smodlaka Tankovi\'{c}, Mirta and Bari\v{c}evi\'{c}, Ana and Geri\'{c}, Marko and Domijan, Ana-Marija and Mari\'{c} Pfannkuchen, Daniela and Ku\v{z}at, Nata\v{s}a and Ujevi\'{c}, Ivana and Kurali\'{c}, Malissa and Ro\v{z}man, Marko and Matkovi\'{c}, Katarina and Novak, Matja\v{z} and \v{Z}egura, Bojana and Pfannkuchen, Martin and Gajski, Goran}, year = {2022}, pages = {12}, DOI = {10.1016/j.envres.2022.114108}, chapter = {114108}, keywords = {Pseudo-nitzschia, Domoic acid, human peripheral blood cells, Cyto/genotoxicity, environmental safety}, journal = {Environmental research}, doi = {10.1016/j.envres.2022.114108}, volume = {214}, issn = {0013-9351}, title = {Characterisation and toxicological activity of three different Pseudo-nitzschia species from the northern Adriatic Sea (Croatia)}, keyword = {Pseudo-nitzschia, Domoic acid, human peripheral blood cells, Cyto/genotoxicity, environmental safety}, chapternumber = {114108} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font