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Ternary Coordination Compound of Copper(II), 1,10- phenanthroline and L-threonine: Interplay of Coordination and Protonation

Ternary coordination compounds of copper(II), amino acids and heterocyclic bases are widely investigated due to their pronounced antiproliferative activity [1, 2]. Such compounds are also interesting for investigation in crystal engineering since they are able to form predictive supramolecular synthons, such as π-stacked heterocyclic bases, or N–HꞏꞏꞏO anion hydrogen bonds. They also form porous architectures making them good candidates for potential application in solvent or gas sorption [1]. In this work, we report synthesis and crystal structure of a novel ternary coordination compound of copper(II), 1, 10-phenanthroline (phen) and L- threonine (HThr). In the asymmetric unit of crystal structure, three different coordination species are present: two cations of a type [Cu(Thr)L(phen)]+ (L = H2O or CH3OH) and an anion [Cu(Thr)(SO4)(phen)]−. Besides coordinated water and methanol molecules, crystallization water and methanol molecules are interconnected through hydrogen bonds forming discrete pockets (13% of the unit cell volume). Crystal structure also contains hydrogensulfate ions which form hydrogen bonds with coordinated sulfate ions (Figure 1).

copper ; crystal structures ; ternary coordination compounds ; threonine

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