engleski

EFFECTS OF HELICOBACTER PYLORI ON FAECAL CALPROTECTIN IN DEVELOPMENT COLORECTAL CARCINOM

Faecal calprotectin (FC) is a known marker of colonic inflammation. There is evidence of elevated FC levels in patients with Helicobacter pylori (HP) infection and in patients with colorectal cancer (CRC). Chronic inflammation and HP have been associated with increased risk for CRC. Aim of this study was to find differences in FC levels in patients with CRC regarding HP infection. Our results confirm the association of chronic colonic inflammation and CRC, but also imply there is an additional effect of HP on colonic inflammation in patients with CRC. Further studies in order to clarify the potential role of FC in patients with HP and CRC are needed.

H pylori Colorectal carcinoma, Faecal calprotectin

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