engleski

B-TCP porous scaffolds with controlable macro- microporosity prepared by PU replication method assisted by vacuum

Nowadays, calcium phosphate (CaP) ceramics are the leading standard of bone grafting materials because of their many useful properties in bone tissue engineering. Their bioactivity can be assigned to their structural similarity to the mineral part of bone and when implanted they act as a suitable scaffold to enhance the growth of bone cells and direct deposition of bone for rapid bone regeneration, that is they are osteoconductive. Research also strongly suggests that the key parameters that play a role in a material’s osteoinductivity, that is the property of a material to grow bone, are microstructural surface properties such as particle size, microporosity, specific surface area and surface roughness. Therefore, control of macro- microporosity is very beneficial. In this study, we report on the influence of vacuum assisted infiltration of PU sponges on microstructure, porosity and compressive strength as opposed to scaffolds fabricated without vacuum infiltration. Starting powders were synthesized through aqueous precipitation and characterized by FTIR and XRD while shaped scaffolds were characterized by SEM, B.E.T. and mechanical testing

Biomaterals, microporous ceramics

nije evidentirano