engleski

Caveolin-1 expression in tissue and cfDNA methylation status in semen plasma of patients with benign prostate hyperplasia and prostate cancer

Caveolin-1 is a protein important for caveolae formation in plasma membrane invaginations. It’s functions include regulation of cell differentiation, apoptosis, cell proliferation, migration, angiogenesis, senescence, endocytosis and interaction with signaling molecules. The expression of this protein significantly differs in BPH and PCa tissue. As for cfDNA methylation, significant differences in DNA methylation of CpG1 between BPH and PCa were demonstrated. CAV1 is a potential non- invasive biomarker for distinguishing BPH and prostate cancer.

prostate cancer ; caveolin-1 ; benign prostate hyperplasia

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