Autosomal STRs in Croatians (CROSBI ID 491133)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Martinović Klarić, Irena ; Peričić, Marijana ; Barać, Lovorka ; Janićijević, Branka ; Kubat, Milovan ; Pavičić, Dino ; Rudan, Igor ; Rudan, Pavao
engleski
Autosomal STRs in Croatians
The aim of this study is to analyze variation of nine autosomal STRs (D3S1358, vWA, FGA, THO1, TPOX, CSF1PO, D5S818, D13S317, D7S820) in Croatian mainland population and 5 Adriatic islands in order to investigate Croatian genetic structure and evaluate the usefulness of the studied loci in regional level genetic differentiation. This investigation demonstrates a substantial genetic homogeneity of the Croatian gene pool as revealed by distribution of allelic frequencies, heterozygosity values, number of alleles and allele size variance, allele and genotype sharing data. Considerable heterogeneity in the degree of differentiation is noted at different loci. Locus TPOX shows the lowest level of heterozygosity (59.75%) and FGA the highest (86.42%). GST based on gene diversity and allele size variance is lowest at VWA locus (0.16% and &#8211 ; 0.33%, respectively) and highest at TPOX locus (0.96% and 2.51%). The average coefficients of gene differentiation based on gene diversity (0.53%) and allele size variance (0.49%) point to low levels of population substructuring. Even though a larger sample sizes for villages within islands could have provided a greater power of autosomal STRs in resolving patterns of microevolutionary structuring at regional level, the greatest discriminating power will certainly result when all classes of genetic markers, paternal, maternal and autosomal, will be jointly considered.
microsatellites; population structure; Croatia
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Podaci o prilogu
104-x.
2003.
objavljeno
Podaci o matičnoj publikaciji
International Anthropological Congress "Anthropology and Society"
Vignerová, Jana ; Riedlová, Jitka ; Bláha, Pavel
Prag: Charles University, Faculty of Science, University of Anthropology and Human Genetics
Podaci o skupu
International Anthropological Congress "Anthropology and Society"
poster
22.05.2003-24.05.2003
Prag, Češka Republika