engleski

Synthesis of N^β-Substituted 1,2- Diazetidin-3-ones by the Ugi Reaction Comprising Chiral α-Hydrazino Acids

We report the synthesis of a structurally diverse library of chiral Nβ-substituted 1, 2-diazetidin- 3- ones by a 4-center 3-component Ugi reaction comprising unprotected α-hydrazino acids. Various isocyanides and carbonyl compounds and both aldehydes and ketones were utilized. In addition, postcondensation modifications at three different sites have been demonstrated.

Chemical reactions ; Inorganic carbon compounds ; Lipids ; Organic compounds ; Ugi reaction ; Hydrazino acids

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