Simultaneous influence of titanate nanomaterials and chitosan on precipitation of calcium phosphate (CROSBI ID 719224)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Erceg, Ina ; Milisav, Ana-Marija ; Strasser, Vida ; Dutour Sikirić, Maja
engleski
Simultaneous influence of titanate nanomaterials and chitosan on precipitation of calcium phosphate
The increased frequency of hard tissue diseases, which commonly can be treated only by implantation, is motivating research of materials’ new innovative designs as well as green and low-cost routes of fabrication. In this sense, composites of calcium phosphates (CaPs) with inorganic nanomaterials or organic macromolecules attract special attention. In addition to replacing missing tissue or enabling its regeneration, they can have improved mechanical properties and/or act as a local drug delivery system [1]. In order for these materials to be functional and to rationalize their design, the interactions between CaPs and additives should be understood. This is very often not the case, and success stories are often a result of a more empirical rather than a systematic approach. To fill this void, in this study the simultaneous influence of titanate nanomaterials and chitosan on the precipitation of CaPs was investigated. Titanate nanomaterials are proposed as additives which can improve CaP mechanical properties, while chitosan is biocompatible [2]. To the best of our knowledge, the studies on the precipitation of CaP in the simultaneous presence of two additives are rare. Four different classes of TiNMs, namely nanoparticles (TiNP), nanowires (TiNW), nanotubes (TiNT), and nanoplates (TiNPl), were synthesized by hydrothermal methods, and their composites with CaPs were synthesized by precipitation from solutions. In order to obtain multifunctional composites, chitosan was added simultaneously with TiNM in the precipitation systems. The progress of precipitation was followed by potentiometric measurements. The precipitated composites were characterized by Fourier transform infrared spectroscopy (FTIR), powder X-ray diffraction (PXRD) and scanning electron microscopy (SEM). The obtained results show that precipitation of CaP in the presence of TiNMs and chitosan can be used as a fast and versatile method for the preparation of CaP/TiNM composites. Neither class of additives had an effect on the structure or composition of the formed composites, either added alone or simultaneously. However, an effect on the morphology of the CaPs was observed. The obtained results will provide a deeper insight into the precipitation processes on nanosurfaces, which will enable a rational approach in synthesis of novel composites for hard tissue regeneration and various other applications.
calcium phosphates ; chitosan ; titanate nanomaterials
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Podaci o prilogu
53-53.
2022.
objavljeno
Podaci o matičnoj publikaciji
4th Croatian Microscopy Congress with nternational Participation: Book of Abstracts
Macan, Jelena ; Kovačević, Goran
Zagreb: Hrvatsko mikroskopijsko društvo ; Institut Ruđer Bošković
978-953-7941-41-3
Podaci o skupu
4th Croatian Microscopy Congress (CMC 2022)
predavanje
18.05.2022-20.05.2022
Poreč, Hrvatska