engleski

CLINICAL EPIDEMIOLOGY OF UPPER URINARY TRACT UROTHELIOMA IN CROATIA BETWEEN 1980 -1990

The 11-year prospective epidemiological study has encompassed 58 cases of upper urinary tract urothelioma, including 21 solitary tumors of renal pelvis, 9 solitary ureteral tumors and 28 multifocal tumors. An analysis of sex, age and residential distribution of patients was carried out as well as their occupation, frequency and distribution of symptoms, test results, tumor locality, "staging", histopathological characteristics and tumor relapses, frequency of simultaneous primary cancer, surgical approach and techniques, intraoperative and postoperative complications, as well as postoperative death rate. The aim of the study is to estabtish the basic clinical and epidemiological parameters important for the assessment of ; the relationship between this disease and risk factors, the clinical picture of the disease, the applicability of diagnostic procedures, the pathological characteristics of the disease and surgical treatment results. This comprehensive procedure is necessary for reassessment of this seldom and in many ways distinctive casuistry, which is particularly important for our national pathology. The participation of patients from the focuses of endemic uropathy amounting to 34.5% and of rural residents amounting to 31.0% indicates the epidemiological distinction of observed group of patients. Poor and frequently unrecognized symptomathology, high relapse rate accompanied by neglecting of recurrent hematuria as well as of constantly positive urinary citology, inadequate surgical results with the postoperative death rate of 15.5% and low 5-year survival rate, call for revision of the recent clinical approach to the upper urinary tract urothelioma.

UROTHELIOMA; CLINICAL EPIDEMIOLOGY

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