Synthesis and antitumor activity of novel 7-chloro- 4-aminoquinoline-benzimidazoles (CROSBI ID 718588)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Krstulović, Luka ; Jukić, Marijana ; Opačak- Bernardi, Teuta ; Bajić, Miroslav ; Glavaš- Obrovac, Ljubica
engleski
Synthesis and antitumor activity of novel 7-chloro- 4-aminoquinoline-benzimidazoles
In our ongoing efforts to design novel antitumor hybrid molecules, novel derivatives of 7-chloro-4- aminoquinoline-benzimidazole have been synthesized, and their antiproliferative activity against tumor cell lines was investigated. All tested compounds showed antiproliferative effects against leukemia and lymphoma cell lines. Strongest activity was observed for compound 1d which also showed no cytotoxic effect on normal cell lines.
quinoline, benzimidazole, antitumor
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Podaci o prilogu
109-109.
2021.
objavljeno
Podaci o matičnoj publikaciji
Marković, Dean ; Meštrović, Ernest ; Namjesnik, Danijel ; Tomašić, Vesna
Zagreb: Hrvatsko kemijsko društvo
2757-0754
Podaci o skupu
27. hrvatski skup kemičara i kemijskih inženjera (27HSKIKI) ; 5. simpozij Vladimir Prelog
poster
05.10.2021-08.10.2021
Rovinj, Hrvatska
