engleski

Non-malignant lesions in clinical thyroid diseases register of University Hospital "Sestre milosrdnice"

Recent nationwide study showed that 8- 15% of Croatian population has endemic goiter. The aim of our retrospective study was to make an analysis of the hospital population during the eighteen year period from 1980 to 1997. We have calculated incidence, sex distribution, and time of the diagnosis for each of the non-malignant thyroid Iesion. The analysis was done using the "Thanatos" computer system developed at the "Sestre milosrdnice" University Hospital. "Thanatos" is a computer data base of the biopsy findings together with the clinical data. There were total 3552 non-malignant thyroid lesions during that period.The most common was goiter: 2098 cases or 59, 1%. Among those there were 256 men, and 1842 women with female to male ratio (F:M) 7, 2:1. Average age (AA) of the men was 49, 7 yr., and AA of the women was 46, 8 yr.There were 979 adenomas (27, 6%): 138 among men (AA=46, 7yr), and 841 among women (AA=44, 5yr.) with F:M=6, 1: 1. There were 247 cases (7%) of the Basedow disease: 23 males (AA=46, 4yr.), and 224 females (AA=37yr) with F:M=9, 7:1. Hashimoto disease was found in 156 cases (4, 4%): 8 men (AA=5 1, 6yr.), and 148 women (AA=49, 8yr.) with F:M= 18, 5: 1. Hyperplasia was the diagnosis in 64 cases (1, 8%): 6 men (AA=35, 2yr.), and 58 women (AA=35, 3yr.) with F:M=9, 6: 1. We have also found five women with the fibroses thyreoiditis (AA=52yr). More then half or 59, 1% of the non-malignant slesions goes to goiter. All non-malignant thyroid lesions are more common in women, especially Hashimoto disease (F:M= 18, 51). Most of the non-malignant thyroid lesions occur during the fourth and fifth decade of life. Hyperplasia is being diagnosed at the average age of 35, 2 yr. in men and 35, 3 in women. Basedow disease in women is being diagnosed at the average age of 37yr

thyroid diseases register; non-malignant lesions

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