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Pregled bibliografske jedinice broj: 1195873

Effect of silver nanoparticles on the precipitation of calcium phosphates


Milisav, Ana-Marija; Erceg, Ina; Strasser, Vida; Dutour Sikirić, Maja
Effect of silver nanoparticles on the precipitation of calcium phosphates // 4th Croatian Microscopy Congress with International Participation : Book of Abstracts / Macan, Jelena ; Kovačević, Goran (ur.).
Zagreb: Croatian Microscopy Society and Ruđer Bošković Institute, 2022. str. 117-117 (poster, domaća recenzija, sažetak, ostalo)


CROSBI ID: 1195873 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Effect of silver nanoparticles on the precipitation of calcium phosphates

Autori
Milisav, Ana-Marija ; Erceg, Ina ; Strasser, Vida ; Dutour Sikirić, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
4th Croatian Microscopy Congress with International Participation : Book of Abstracts / Macan, Jelena ; Kovačević, Goran - Zagreb : Croatian Microscopy Society and Ruđer Bošković Institute, 2022, 117-117

ISBN
978-953-7941-41-3

Skup
4th Croatian Microscopy Congress with International Participation

Mjesto i datum
Poreč, Hrvatska, 18.05.2022. - 20.05.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
calcium phosphates ; silver nanoparticles

Sažetak
Considering the increasing number of post- operative infections caused by antibiotic- resistant bacteria, research of therapeutic alternatives attracts special attention. The development of bioactive antimicrobial coatings for orthopaedic implants is of particular interest, as they can act locally and could reduce the use of oral antibiotics. In this sense, composite coatings based on calcium phosphates (CaPs) and metal or metal oxide nanomaterials have great potential, since CaPs occur naturally in the human body and inorganic nanoparticles do not in principle promote bacterial resistance [1]. Among different nanomaterials, silver nanoparticles (AgNPs) have shown optimal antimicrobial properties and cytocompatibility. In addition, their incorporation into various composite coatings within the organic or inorganic matrix was found to be beneficial, particularly with respect to their potential for controlled release system formulation in situ [2]. This study aimed to develop a green synthesis route for the preparation of novel CaP composites with AgNPs based on the precipitation of CaPs in the presence of AgNPs with different capping agents at different concentrations. For this purpose, two types of AgNPs were synthesised: one stabilised with polyvinylpyrrolidone (PVPAgNP) and the other stabilised with sodium bis(2-ethylhexyl) sulfosuccinate (AOTAgNP) [3]. The progress of precipitation was followed by monitoring the pH changes in the precipitation systems over time. The precipitates obtained after one hour of reaction time were filtered and characterised by powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The results showed that calcium-deficient hydroxyapatite (CaDHA) was formed both in the absence and presence of AgNPs. SEM micrographs revealed a significant difference in the morphology of the precipitates formed in the different systems, indicating the important influence of the stabilising agent, i.e., the surface composition of the NPs. The results of this study indicate that the formation of CaP composites with metallic nanoparticles should be studied in depth as various parameters can differently affect the process and ultimately the properties of the formed materials. The elucidation of this process is of great importance for the development of improved orthopaedic implants.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekti:
EK-861138 - Integrirane antimikrobne metodologije za ortopedsku primjenu (AIMed) (Dutour Sikirić, Maja, EK ) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb


Citiraj ovu publikaciju:

Milisav, Ana-Marija; Erceg, Ina; Strasser, Vida; Dutour Sikirić, Maja
Effect of silver nanoparticles on the precipitation of calcium phosphates // 4th Croatian Microscopy Congress with International Participation : Book of Abstracts / Macan, Jelena ; Kovačević, Goran (ur.).
Zagreb: Croatian Microscopy Society and Ruđer Bošković Institute, 2022. str. 117-117 (poster, domaća recenzija, sažetak, ostalo)
Milisav, A., Erceg, I., Strasser, V. & Dutour Sikirić, M. (2022) Effect of silver nanoparticles on the precipitation of calcium phosphates. U: Macan, J. & Kovačević, G. (ur.)4th Croatian Microscopy Congress with International Participation : Book of Abstracts.
@article{article, author = {Milisav, Ana-Marija and Erceg, Ina and Strasser, Vida and Dutour Sikiri\'{c}, Maja}, year = {2022}, pages = {117-117}, keywords = {calcium phosphates, silver nanoparticles}, isbn = {978-953-7941-41-3}, title = {Effect of silver nanoparticles on the precipitation of calcium phosphates}, keyword = {calcium phosphates, silver nanoparticles}, publisher = {Croatian Microscopy Society and Ru\djer Bo\v{s}kovi\'{c} Institute}, publisherplace = {Pore\v{c}, Hrvatska} }
@article{article, author = {Milisav, Ana-Marija and Erceg, Ina and Strasser, Vida and Dutour Sikiri\'{c}, Maja}, year = {2022}, pages = {117-117}, keywords = {calcium phosphates, silver nanoparticles}, isbn = {978-953-7941-41-3}, title = {Effect of silver nanoparticles on the precipitation of calcium phosphates}, keyword = {calcium phosphates, silver nanoparticles}, publisher = {Croatian Microscopy Society and Ru\djer Bo\v{s}kovi\'{c} Institute}, publisherplace = {Pore\v{c}, Hrvatska} }




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