engleski

DISTRIBUTION OF THYROID CARCINOMAS ACCORDING TO AGE, SEX AND PATHOLOGICAL DIAGNOSIS - COMPARISON OF TWO FIVE-YEAR PERIODS

Aim of the study was to investigate possible changes in the prevalence of various types of thyroid carcinomas during two tive-year periods. For that purpose we have reviewed all surgical pathology files between 1987 and 1996. Our interest was limited to the following pathological types of thyroid carcinomas: a) difierentiated thyroid carcinomas /DTC/, (subdivided to papillary /PC/ and follicular carcinoma /FC/) ; b) medullary thyroid carcinoma IMTC/ ; and c) anaplastic thyroid carcinoma /ATC/. During the period 1987-91. we analysed 88 operated thyroid carcinomas. There were 76 DTC (86, 3%), which consisted of 701'C.' (92, 1% of DTC, and 79, 5% of total) and 6 cases of F(' (7, 9% of DTC, and 6, 8% of total). Female to male ratio among D'fC was 3:1. MTC was detected in 7 cases (8% of total), with female to male ratio 2, 5:1. ATC was found in 5 cases (5, 7% of total, 3 females and 2 males). (n the period 1992-96, 84 patients underwent surgery due to thyroid malignancy. DTC was diagnosed in 71 cases (84, 5%), with 64 T(' (90, 1% of DTC, and 76, 2% of total), and 7 patients with F'C (8, 9% of DTC, and 8, 3% of total). Female to male ratio among DTC was 2, 7:1. MTC was found in 10 patients (12% of total), with female to male ratio 1:1. ATC had 3 patients (3, 5% of total, 1 female and 2 males). As presented, prevalence of DTC in both sexes was not significantly changed during two five-year periods. Certain increase of the prevalence of MTC was observed between two compared periods, with large shift in female to male ratio, indicating increase of prevalence among male patients. Finally, relative decrease in prevalence was observed for ATC. In conclusion we may say that although no major changes in the prevalence of DTC were observed in the last decade, mild increase of MTC (with lowering of female to male ratio) certainly warrants further epidemiological investigations.

THYROID CARCINOMAS; DISTRIBUTION

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