engleski

CHORANGIOMA PLACENTAE

Chorangioma placentae was considered as a very rare tumour of placenta, but in the recent literature its frequency is about 1% (1). Being classified as an haemangioma, its histological appearance is variable and pleomorphic. It could be divided into endotheliomatous, capillarious, cavernous and fibromatous form, from which the capillarious is the most common of all chorangiomas. Chorangiomata probably arise as malformations of the primitive angioblastic tissue of the early palcenta. There are many reported instances of risk pregnancies, which were accompanied with the placental chorangiomata, such as hydramnion, pre-eclampsia, antepartum bleeding, premature onset of labour, but the overall perinatal mortality is only minimal increased. On the contrary, clinically significant chorangiomas, greater then 4 cm, are associated with fetal loss rate of approximately 40%. Recently, we have observed chorangioma as an incidental finding during the routine macroscopic examination of the placenta of the 28 year primipara whose pregnancy was clinically normal. She was admitted to the hospital for labour at 40 weeks of gestation. Pregnancy, labor and delivery were uncomplicated. She was delivered of a healthy female child measuring 52 cm, 3500 g, with Apgar score 1=9, 5=10. Placenta measured 16:16:2, 5 em, 350 g, with centrally attached umbilical cord and radially distributed alantoic blood vessels. Solitary, ovoid mass was observed on the fetal side of the placenta, measuring 4 cm in greatest diameter with soft and bright red cut surface. Histologically, our case of chorangioma was of the capillarious appearance, and in this manner, the immunohistoreactivity to UEA lectin was strongly expressed in tumours tissue. Despite to the clinical data, we believe that transient early pregnancy hypoxia have triggered a circumscribed excessive angioblastic proliferation in the placental tissue.

CHORANGIOMA PLACENTAE

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