engleski

Which demographic disease related variables may be predictors of quality of life in psoriatic arthritis patients?

Psoriatic arthritis (PsA) patients may face challenges other than skin disease, arthralgias, synovitis or dactylitis. These patients experience considerable disability and impaired quality of life, including sleep problems, depression/anxiety and problems in intimate life. To assess if age at onset of PsA and psoriasis, duration of PsA and psoriasis severity of psoriasis, functional ability and disease activity are predictors of quality of life in PsA patients. The study was conducted in two visits with five years period in between at the outpatient clinic of the rheumtology departments in two tertiary university hospitals, in Zagreb and Split. A total of 114 PsA patients (61 men, 53 women) were enrolled in the phase 1, while phase 2 included 104 patients (56 men, 48 women). Practising experienced rheumatologists collected demographic data and history of diseases (age, gender, age of diagnosis, duration of psoriasis and PsA). HAQ was used to assesses function and DAS28 for disease activity. For assessing quality of life patients filled SF36. Methods of descriptive statistics and canonical regression were used in this research.Mean age of patients in phase 1 was 57, 3±11, 1 years (men 57, 81 years, women 56, 83years) and mean age of patients in phase 2 was 60, 1±11, 3 years (men 60, 1 years, women 60, 1years). Mean duration of psoriasis in phase 1 was 211, 9±147, 1 months and in phase 2 was 251, 6±153, 9 months, while mean duration of PsA in phase 1 was 132, 5±113, 6 months and in phase 2 was 171, 7±108, 4 months. Canonical regression was performed in both phases and showed that age of PsA diganosis and duration of PsA were signifi cantly associated with worse functional ability, but not with the quality of life of PsA patients.Based on the result of this research, functional ability of PsA patients depends on age at diagnosis and disease duration which could be considered as the predictors of functional ability in PsA patients

psoriatic arthritis ; disease duration ; quality of life ; functional ability

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