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Influence of adiponectin and glycated hemoglobin in prediction of major adverse cardiac events in non-diabetic patients after ST-segment elevation myocardial infarction

Microvascular dysfunction and glucometabolic dysregulation are associated with poor prognosis after acute myocardial infarction. It has been reported that adiponectin modulates vascular homeostasis and protects against cardiometabolic disorders. Hypoadiponectiemia is associated with left ventricular remodeling and poor clinical outcome. This study aimed to investigate the association of adiponectin and HbA1C with major adverse cardiac events in non-diabetic patients who survived ST-elevation myocardial infarction. The study enrolled prospectively 73 non-diabetic patients who experienced STEMI infarction. We measured the level of adipose tin and HbA1C in all patients. The subject were divided into two groups: 37 patients with elevated HbA1C and 36 patients with normal levels of HbA1C. Cardiac structure and function were assessed using two-dimensional transthoracic echocardiography. In a one-year follow-up, the study subject were observed for major adverse cardiac events (MACE)........

ST Elevation Myocardial Infarction ; Hypoadiponectinemia ; Adiponectin ; Glycated Hemoglobin A ; Ventricular Remodeling ; Homeostasis

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