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Pregled bibliografske jedinice broj: 119057

Gene therapy: concept, curret status, moral and ethical aspects


Pavelić, Jasminka; Herak Bosnar, Maja; Kralj, Marijeta
Gene therapy: concept, curret status, moral and ethical aspects // Periodicum biologorum, 106 (2004), 3; 239-244 (međunarodna recenzija, pregledni rad, znanstveni)


Naslov
Gene therapy: concept, curret status, moral and ethical aspects
(Gene therapy: concept, current status, moral and ethical aspects)

Autori
Pavelić, Jasminka ; Herak Bosnar, Maja ; Kralj, Marijeta

Izvornik
Periodicum biologorum (0031-5362) 106 (2004), 3; 239-244

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Gene therapy

Sažetak
To date, many diseases of genetic origin remain untreated. A potential approach to the treatment of genetic disorders in man is gene therapy, a technique whereby the absent of faulty gene is replaced by a working one, so that body can make the correct protein and consequently eliminate the root cause of the disease. The fundamental issue of gene therapy is the problem of introducing the therapeutic DNA or RNA into correct cell or tissue and subsequent expression of the protein in the host. However, this is far from to be resolved question, being therefore the main hurdle in gene therapy application. Novel therapeutic approaches are required that offer greater potential and selectivty and that act by mechanisms that are not the subject to cross-resistance when combine with tandart therapies.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
0098092

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • Excerpta Medica