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Pregled bibliografske jedinice broj: 1190354

Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study


Karmelić, Ivana; Salarić, Ivan; Baždarić, Ksenija; Rožman, Marko; Zajc, Ivan; Mravak-Stipetić, Marinka; Bago, Ivona; Brajdić, Davor; Lovrić, Jasna; Macan, Darko
Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study // Dentistry journal, 10 (2022), 4; 70, 10 doi:10.3390/dj10040070 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1190354 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study

Autori
Karmelić, Ivana ; Salarić, Ivan ; Baždarić, Ksenija ; Rožman, Marko ; Zajc, Ivan ; Mravak-Stipetić, Marinka ; Bago, Ivona ; Brajdić, Davor ; Lovrić, Jasna ; Macan, Darko

Izvornik
Dentistry journal (2304-6767) 10 (2022), 4; 70, 10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
oral cancer ; early diagnosis ; biomarkers ; saliva

Sažetak
Oral squamous cell carcinoma (OSCC) is frequently diagnosed in the advanced stages. The purpose of this paper is to determine the salivary values of SCCA1, SCCA2 and TROP2 in patients with T1N0M0 OSCC and to compare them with the values obtained from healthy individuals. Unstimulated (UWS) and stimulated (SWS) saliva was sampled from 29 patients with T1N0M0 OSCC and 29 sex- and age- matched healthy individuals. Statistical difference was observed in SCCA1 and SCCA2 levels both in UWS and SWS samples. TROP2 was not measurable in most of the salivary samples. Both SCCA1 and SCCA2 could represent potential biomarkers for the early-stage OSCC. Research on a larger sample and biomarker validation is needed to assess the clinical potential of SCCA1 and SCCA2 in the OSCC early diagnostics.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
HRZZ-IP-2014-09-9376 - Izolacija, kvantifikacija i kinetika salivarnih Ap4A, SCCA i TROP2 kod pacijenata s oralnim karcinomom i potencijalno malignim poremećajima (OC Sal TM) (Macan, Darko, HRZZ - 2014-09) ( POIROT)

Ustanove:
Medicinski fakultet, Rijeka,
Stomatološki fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Medicinski fakultet, Zagreb,
Klinička bolnica "Dubrava",
Sveučilište u Zagrebu,
Sveučilište u Rijeci

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com doi.org fulir.irb.hr

Citiraj ovu publikaciju:

Karmelić, Ivana; Salarić, Ivan; Baždarić, Ksenija; Rožman, Marko; Zajc, Ivan; Mravak-Stipetić, Marinka; Bago, Ivona; Brajdić, Davor; Lovrić, Jasna; Macan, Darko
Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study // Dentistry journal, 10 (2022), 4; 70, 10 doi:10.3390/dj10040070 (međunarodna recenzija, članak, znanstveni)
Karmelić, I., Salarić, I., Baždarić, K., Rožman, M., Zajc, I., Mravak-Stipetić, M., Bago, I., Brajdić, D., Lovrić, J. & Macan, D. (2022) Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study. Dentistry journal, 10 (4), 70, 10 doi:10.3390/dj10040070.
@article{article, author = {Karmeli\'{c}, Ivana and Salari\'{c}, Ivan and Ba\v{z}dari\'{c}, Ksenija and Ro\v{z}man, Marko and Zajc, Ivan and Mravak-Stipeti\'{c}, Marinka and Bago, Ivona and Brajdi\'{c}, Davor and Lovri\'{c}, Jasna and Macan, Darko}, year = {2022}, pages = {10}, DOI = {10.3390/dj10040070}, chapter = {70}, keywords = {oral cancer, early diagnosis, biomarkers, saliva}, journal = {Dentistry journal}, doi = {10.3390/dj10040070}, volume = {10}, number = {4}, issn = {2304-6767}, title = {Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study}, keyword = {oral cancer, early diagnosis, biomarkers, saliva}, chapternumber = {70} }
@article{article, author = {Karmeli\'{c}, Ivana and Salari\'{c}, Ivan and Ba\v{z}dari\'{c}, Ksenija and Ro\v{z}man, Marko and Zajc, Ivan and Mravak-Stipeti\'{c}, Marinka and Bago, Ivona and Brajdi\'{c}, Davor and Lovri\'{c}, Jasna and Macan, Darko}, year = {2022}, pages = {10}, DOI = {10.3390/dj10040070}, chapter = {70}, keywords = {oral cancer, early diagnosis, biomarkers, saliva}, journal = {Dentistry journal}, doi = {10.3390/dj10040070}, volume = {10}, number = {4}, issn = {2304-6767}, title = {Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study}, keyword = {oral cancer, early diagnosis, biomarkers, saliva}, chapternumber = {70} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)
  • Scopus
  • MEDLINE


Citati:





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