engleski

Reply: Systemic Inflammatory Markers as Predictors of Postoperative Complications and Survival in Patients With Advanced Head and Neck Squamous Cell Carcinoma Undergoing Free-Flap Reconstruction

Purpose: The aim of this study was to determine the prognostic value of systemic inflammatory indices as factors for postoperative complications and survival in patients with advanced stages of p16-negative HNSCC undergoing free flap reconstruction. Methods: A retrospective cohort study. The primary predictor variables were inflammatory markers ; neutrophil, lymphocyte, monocyte, and platelet count, neutrophil- lymphocyte (NLR), platelet-lymphocyte (PLR), lymphocyte-monocyte (LMR), derived neutrophil- lymphocyte ratio (dNLR), systemic immune- inflammation (SII) and systemic inflammatory marker index (SIM). Multivariate regression analyses were used to measure the associations between systemic inflammatory indices and overall and disease-free survival as a primary outcome and occurrence of postoperative complications as a secondary outcome measure. Response to a LTE.

free flap ; anthopometry ; survival ; inflammatory marker

nije evidentirano