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Antioxidant and Anti-Atherogenic Activities of Essential Oils from Myrtus communis L. and Laurus nobilis L. in Rat (CROSBI ID 308046)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Odeh, Dyana ; Oršolić, Nada ; Berendika, Marija ; Ðikić, Domagoj ; Domjanić Drozdek, Sandra ; Balbino, Sandra ; Repajić, Maja ; Dragović-Uzelac, Verica ; Jurčević Landeka, Irena Antioxidant and Anti-Atherogenic Activities of Essential Oils from Myrtus communis L. and Laurus nobilis L. in Rat // Nutrients, 14 (2022), 7; 1465, 31. doi: doi.org/10.3390/nu14071465

Podaci o odgovornosti

Odeh, Dyana ; Oršolić, Nada ; Berendika, Marija ; Ðikić, Domagoj ; Domjanić Drozdek, Sandra ; Balbino, Sandra ; Repajić, Maja ; Dragović-Uzelac, Verica ; Jurčević Landeka, Irena

engleski

Antioxidant and Anti-Atherogenic Activities of Essential Oils from Myrtus communis L. and Laurus nobilis L. in Rat

Essential oils (EOs) from aromatic and medicinal plants, such as myrtle (Myrtus communis L.) and Laurel (Laurus nobilis L.), are gaining popularity as a potential ingredient in functional foods and nutraceuticals. This study aims to investigate whether the essential oils (EOs) could be effective in weight control, antioxidative and antilipidemic status of rats by affecting microbiota and its enzymes activity and whether changes in intestinal enzyme activity affect the health of rats. The intragastric application of laurel and myrtle EOs to rats for two weeks affects weight loss, reduces glycolytic activity, lipid parameters (cholesterol, triglycerides, low- density lipoprotein cholesterol (LDL-C) and very low-density lipoprotein cholesterol (VLDL-C)) and atherogenic indicators, leading to cardiovascular protection. Laurel EO can be an excellent candidate for the treatment of drug-induced obesity and related diseases, since it affects lipid metabolism in the liver and inhibits the enzymes responsible for the metabolism of carbohydrates into glucose in the digestive tract, leading to weight loss. In contrast, myrtle EO shows a better antioxidant capacity in most tissues, except kidneys, where it causes a pro- oxidative effect, compared to laurel EO. Myrtle EO increases the permeability and instability of the erythrocyte membrane, resulting in a loss of selectivity for the entry of toxic substances into the cell. On the other hand, myrtle EO leads to intestinal inflammation by reducing the number of probiotic bacteria and increasing Enterobacter.

myrtle and laurel essential oils ; lipid parameters ; atherogenic indicators ; antioxidative activity in tissue ; antiatherogenic activity

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Podaci o izdanju

14 (7)

2022.

1465

31

objavljeno

2072-6643

doi.org/10.3390/nu14071465

Povezanost rada

Biologija, Biotehnologija

Poveznice
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