Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1187288

MiR-7 in Cancer Development


Korać, Petra; Antica, Mariastefania; Matulić, Maja
MiR-7 in Cancer Development // Biomedicines, 9 (2021), 3; 325, 20 doi:10.3390/biomedicines9030325 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1187288 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
MiR-7 in Cancer Development

Autori
Korać, Petra ; Antica, Mariastefania ; Matulić, Maja

Izvornik
Biomedicines (2227-9059) 9 (2021), 3; 325, 20

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
microRNAs ; miR-7 ; gene expression ; tumor suppressor ; cancer cell

Sažetak
MicroRNAs (miRNAs) are short non-coding RNA involved in the regulation of specific mRNA translation. They participate in cellular signaling circuits and can act as oncogenes in tumor development, so-called oncomirs, as well as tumor suppressors. miR-7 is an ancient miRNA involved in the fine-tuning of several signaling pathways, acting mainly as tumor suppressor. Through downregulation of PI3K and MAPK pathways, its dominant role is the suppression of proliferation and survival, stimulation of apoptosis and inhibition of migration. Besides these functions, it has numerous additional roles in the differentiation process of different cell types, protection from stress and chromatin remodulation. One of the most investigated tissues is the brain, where its downregulation is linked with glioblastoma cell proliferation. Its deregulation is found also in other tumor types, such as in liver, lung and pancreas. In some types of lung and oral carcinoma, it can act as oncomir. miR-7 roles in cell fate determination and maintenance of cell homeostasis are still to be discovered, as well as the possibilities of its use as a specific biotherapeutic.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekti:
HRZZ-IP-2020-02-2431 - Obnova timusa za preciznu medicinu u liječenju tumora i leukemija (THYMINNOVA) (Antica, Mariastefania, HRZZ - 2020-02) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb

Profili:

Avatar Url Mariastefania Antica (autor)

Avatar Url Petra Korać (autor)

Avatar Url Maja Matulić (autor)

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com fulir.irb.hr

Citiraj ovu publikaciju:

Korać, Petra; Antica, Mariastefania; Matulić, Maja
MiR-7 in Cancer Development // Biomedicines, 9 (2021), 3; 325, 20 doi:10.3390/biomedicines9030325 (međunarodna recenzija, članak, znanstveni)
Korać, P., Antica, M. & Matulić, M. (2021) MiR-7 in Cancer Development. Biomedicines, 9 (3), 325, 20 doi:10.3390/biomedicines9030325.
@article{article, author = {Kora\'{c}, Petra and Antica, Mariastefania and Matuli\'{c}, Maja}, year = {2021}, pages = {20}, DOI = {10.3390/biomedicines9030325}, chapter = {325}, keywords = {microRNAs, miR-7, gene expression, tumor suppressor, cancer cell}, journal = {Biomedicines}, doi = {10.3390/biomedicines9030325}, volume = {9}, number = {3}, issn = {2227-9059}, title = {MiR-7 in Cancer Development}, keyword = {microRNAs, miR-7, gene expression, tumor suppressor, cancer cell}, chapternumber = {325} }
@article{article, author = {Kora\'{c}, Petra and Antica, Mariastefania and Matuli\'{c}, Maja}, year = {2021}, pages = {20}, DOI = {10.3390/biomedicines9030325}, chapter = {325}, keywords = {microRNAs, miR-7, gene expression, tumor suppressor, cancer cell}, journal = {Biomedicines}, doi = {10.3390/biomedicines9030325}, volume = {9}, number = {3}, issn = {2227-9059}, title = {MiR-7 in Cancer Development}, keyword = {microRNAs, miR-7, gene expression, tumor suppressor, cancer cell}, chapternumber = {325} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font