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Pregled bibliografske jedinice broj: 1187264

Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action


Rastija, Vesna; Vrandečić, Karolina; Ćosić, Jasenka; Kanižai Šarić, Gabriella; Majić, Ivana; Agić, Dejan; Šubarić, Domagoj; Karnaš, Maja; Bešlo, Drago; Komar, Mario; Molnar, Maja
Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action // Molecules, 27 (2022), 2196, 17 doi:10.3390/ molecules27072196 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1187264 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action
(Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action)

Autori
Rastija, Vesna ; Vrandečić, Karolina ; Ćosić, Jasenka ; Kanižai Šarić, Gabriella ; Majić, Ivana ; Agić, Dejan ; Šubarić, Domagoj ; Karnaš, Maja ; Bešlo, Drago ; Komar, Mario ; Molnar, Maja

Izvornik
Molecules (1420-3049) 27 (2022); 2196, 17

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
coumarins ; plant protection ; biological activity ; molecular docking ; toxicity ; acetylcholinesterase

Sažetak
Coumarin derivatives have been reported as strong antifungal agents against various phytopathogenic fungi. In this study, inhibitory effects of nine coumarinyl Schiff bases were evaluated against the plant pathogenic fungi (Fusarium oxysporum f. sp. lycopersici, Fusarium culmorum, Macrophomina phaseolina and Sclerotinia sclerotiourum). The compounds were demonstrated to be efficient antifungal agents against Macrophomina phaseolina. The results of molecular docking on the six enzymes related to the antifungal activity suggested that the tested compounds act against plant pathogenic fungi, inhibiting plant cell- wall-degrading enzymes such as endoglucanase I and pectinase. Neither compound exhibited inhibitory effects against two beneficial bacteria (Bacillus mycoides and Bradyrhizobium japonicum) and two entomopathogenic nematodes. However, compound 9 was lethal (46.25%) for nematode Heterorhabditis bacteriophora and showed an inhibitory effect against acetylcholinesterase (AChE) (31.45%), confirming the relationship between these two activities. Calculated toxicity and the pesticide- likeness study showed that compound 9 was the least lipophilic compound with the highest aquatic toxicity. A molecular docking study showed that compounds 9 and 8 bind directly to the active site of AChE. Coumarinyl Schiff bases are promising active components of plant protection products, safe for the environment, human health, and nontarget organisms.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Poljoprivreda (agronomija)



POVEZANOST RADA


Projekti:
HRZZ-UIP-2017-05-6593 - Zelene tehnologije u sintezi heterocikličkih spojeva (GREENNESS) (Molnar, Maja, HRZZ ) ( POIROT)
EK-EFRR-KK.01.1.1.01.0005 - Znanstveni centar izvrsnosti za bioraznolikost i molekularno oplemenjivanje bilja (ZCI CroP-BioDiv) (Šatović, Zlatko; Liber, Zlatko, EK - KK.01.1.1.01) ( POIROT)

Ustanove:
Fakultet agrobiotehničkih znanosti Osijek,
Prehrambeno-tehnološki fakultet, Osijek

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi www.mdpi.com

Citiraj ovu publikaciju:

Rastija, Vesna; Vrandečić, Karolina; Ćosić, Jasenka; Kanižai Šarić, Gabriella; Majić, Ivana; Agić, Dejan; Šubarić, Domagoj; Karnaš, Maja; Bešlo, Drago; Komar, Mario; Molnar, Maja
Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action // Molecules, 27 (2022), 2196, 17 doi:10.3390/ molecules27072196 (međunarodna recenzija, članak, znanstveni)
Rastija, V., Vrandečić, K., Ćosić, J., Kanižai Šarić, G., Majić, I., Agić, D., Šubarić, D., Karnaš, M., Bešlo, D., Komar, M. & Molnar, M. (2022) Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action. Molecules, 27, 2196, 17 doi:10.3390/ molecules27072196.
@article{article, author = {Rastija, Vesna and Vrande\v{c}i\'{c}, Karolina and \'{C}osi\'{c}, Jasenka and Kani\v{z}ai \v{S}ari\'{c}, Gabriella and Maji\'{c}, Ivana and Agi\'{c}, Dejan and \v{S}ubari\'{c}, Domagoj and Karna\v{s}, Maja and Be\v{s}lo, Drago and Komar, Mario and Molnar, Maja}, year = {2022}, pages = {17}, DOI = {10.3390/ molecules27072196}, chapter = {2196}, keywords = {coumarins, plant protection, biological activity, molecular docking, toxicity, acetylcholinesterase}, journal = {Molecules}, doi = {10.3390/ molecules27072196}, volume = {27}, issn = {1420-3049}, title = {Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action}, keyword = {coumarins, plant protection, biological activity, molecular docking, toxicity, acetylcholinesterase}, chapternumber = {2196} }
@article{article, author = {Rastija, Vesna and Vrande\v{c}i\'{c}, Karolina and \'{C}osi\'{c}, Jasenka and Kani\v{z}ai \v{S}ari\'{c}, Gabriella and Maji\'{c}, Ivana and Agi\'{c}, Dejan and \v{S}ubari\'{c}, Domagoj and Karna\v{s}, Maja and Be\v{s}lo, Drago and Komar, Mario and Molnar, Maja}, year = {2022}, pages = {17}, DOI = {10.3390/ molecules27072196}, chapter = {2196}, keywords = {coumarins, plant protection, biological activity, molecular docking, toxicity, acetylcholinesterase}, journal = {Molecules}, doi = {10.3390/ molecules27072196}, volume = {27}, issn = {1420-3049}, title = {Effects of coumarinyl Schiff bases against phytopathogenic fungi, the soil-beneficial bacteria and entomopathogenic nematodes: Deeper insight into the mechanism of action}, keyword = {coumarins, plant protection, biological activity, molecular docking, toxicity, acetylcholinesterase}, chapternumber = {2196} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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