hrvatski

Klinička primjena piperacilina/tazobaktama

Piperacillin/tazobactam is the most effective combination of penicillin and beta-lactamase inhibitors in the treatment of infections caused by strains that excrete beta-lactamase of wider spectrum. In the hospital setting it is proved to reduce the risk from selecting strains that produce wide spectrum beta-lactamases, so that its administration contributes to decrease in the antimicrobial resistance rates. In the period from 2000 to 2002, 23 hospitalized patients with complicated urinary tract infections were treated with piperacillin/tazobactam at the University Hospital for Infectious Diseases "Dr. Fran Mihaljević", in Zagreb. A total of 20 patients were cured, and three experienced a relapse. Although piperacillin/tazobactam is one of the most expensive antimicrobial drugs, looking long-term, we believe that in certain patients it should be administered more often.

piperacilin/tazobaktam; uroinfekcije

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