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Pregled bibliografske jedinice broj: 1184713

Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights


Šudomová, Miroslava; Kateřina Berchová-Bímová; Alena Mazurakova; Dunja Šamec; Peter Kubatka; Sherif T.S. Hassan
Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights // Viruses-Basel, 14 (2022), 3; 592, 19 doi:10.3390/v1403059 (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights

Autori
Šudomová, Miroslava ; Kateřina Berchová-Bímová ; Alena Mazurakova ; Dunja Šamec ; Peter Kubatka ; Sherif T.S. Hassan

Izvornik
Viruses-Basel (1999-4915) 14 (2022), 3; 592, 19

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
flavonoids ; herpes simplex virus ; HSV-1 ; HSV-2 ; varicella-zoster virus ; Epstein–Barr virus ; human cytomegalovirus ; Kaposi sarcoma-associated herpesvirus ; mechanisms of action ; nervous system ; neurological diseases

Sažetak
Human herpesviruses (HHVs) are large DNA viruses with highly infectious characteristics. HHVs can induce lytic and latent infections in their host, and most of these viruses are neurotropic, with the capacity to generate severe and chronic neurological diseases of the peripheral nervous system (PNS) and central nervous system (CNS). Treatment of HHV infections based on strategies that include natural products-derived drugs is one of the most rapidly developing fields of modern medicine. Therefore, in this paper, we lend insights into the recent advances that have been achieved during the past five years in utilizing flavonoids as promising natural drugs for the treatment of HHVs infections of the nervous system such as alpha-herpesviruses (herpes simplex virus type 1, type 2, and varicella-zoster virus), beta- herpesviruses (human cytomegalovirus), and gamma- herpesviruses (Epstein–Barr virus and Kaposi sarcoma-associated herpesvirus). The neurological complications associated with infections induced by the reviewed herpesviruses are emphasized. Additionally, this work covers all possible mechanisms and pathways by which flavonoids induce promising therapeutic actions against the above- mentioned herpesviruses.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Biotehnologija



POVEZANOST RADA


Projekti:
NadSve-Sveučilište Sjever-UNIN-BIOTEH-21-1-1 - Određivanje biološke aktivnosti biljnih ekstrakata i metabolita (Šamec, Dunja, NadSve - Natječaj za potpore znanstvenim istraživanjima i umjetničkom radu Sveučilišta Sjever u 2021. godini) ( POIROT)

Ustanove:
Sveučilište Sjever, Koprivnica

Profili:

Avatar Url Dunja Šamec (autor)

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi www.mdpi.com

Citiraj ovu publikaciju:

Šudomová, Miroslava; Kateřina Berchová-Bímová; Alena Mazurakova; Dunja Šamec; Peter Kubatka; Sherif T.S. Hassan
Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights // Viruses-Basel, 14 (2022), 3; 592, 19 doi:10.3390/v1403059 (međunarodna recenzija, pregledni rad, znanstveni)
Šudomová, M., Kateřina Berchová-Bímová, Alena Mazurakova, Dunja Šamec, Peter Kubatka & Sherif T.S. Hassan (2022) Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights. Viruses-Basel, 14 (3), 592, 19 doi:10.3390/v1403059.
@article{article, author = {\v{S}udomov\'{a}, Miroslava}, year = {2022}, pages = {19}, DOI = {10.3390/v1403059}, chapter = {592}, keywords = {flavonoids, herpes simplex virus, HSV-1, HSV-2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, Kaposi sarcoma-associated herpesvirus, mechanisms of action, nervous system, neurological diseases}, journal = {Viruses-Basel}, doi = {10.3390/v1403059}, volume = {14}, number = {3}, issn = {1999-4915}, title = {Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights}, keyword = {flavonoids, herpes simplex virus, HSV-1, HSV-2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, Kaposi sarcoma-associated herpesvirus, mechanisms of action, nervous system, neurological diseases}, chapternumber = {592} }
@article{article, author = {\v{S}udomov\'{a}, Miroslava}, year = {2022}, pages = {19}, DOI = {10.3390/v1403059}, chapter = {592}, keywords = {flavonoids, herpes simplex virus, HSV-1, HSV-2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, Kaposi sarcoma-associated herpesvirus, mechanisms of action, nervous system, neurological diseases}, journal = {Viruses-Basel}, doi = {10.3390/v1403059}, volume = {14}, number = {3}, issn = {1999-4915}, title = {Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights}, keyword = {flavonoids, herpes simplex virus, HSV-1, HSV-2, varicella-zoster virus, Epstein–Barr virus, human cytomegalovirus, Kaposi sarcoma-associated herpesvirus, mechanisms of action, nervous system, neurological diseases}, chapternumber = {592} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





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