engleski

HSS-GC-FID analysis of residual solvents in food supplements used in the treatment of inflammatory bowel disease

There is an ever-increasing number of food supplements on the global market - products containing concentrated sources of nutrients intended for supplementing the intake of those nutrients from a normal diet. However, due to loose legal regulations in many countries, these products do not undergo the same quality control other medicinal products do. Some of these food supplements may pose public health risks due to the presence of residual solvents in them not being properly reported. Residual solvents are volatile organic chemical substances that may have been used or produced in the preparation of a medicinal product. According to the Globally Harmonized System (GHS) Hazard Classification they are classified from Class 1 to Class 3 based on their potential dangers for human health. In order to determine the presence of residual solvents in food supplements used for the treatment of inflammatory bowel disease method <467> defined by the United States Pharmacopeia was used. Multiple samples from the Croatian market were prepared and analysed using headspace gas chromatography/flame ionization detection (HS-GC-FID) and then compared with chromatograms of analysed standards containing Class 2A, Class 2B, and Class 3 residual solvents, as defined by the GHS Classification.

Turmeric ; Gass chromatography ; Residual solvents

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