engleski

Overview of electroactive and conductive polymers and their use in biomedicine as electrospun bioscaffolds for tissue and nerve repair.

Electroactive/conductive polymers (EAP/ECP) are showing good results as medical textiles for tissue and neural engineering. Applying curent through electroactive textile cells show promising results, where electric stimuly helps faster and better growth of cells on textile scaffolds. Because of their electrical conductivity textiles made of electroactive polymers are great for mimicking real body enviroment where cells are electricly stimulated for growth. Electrical signals are produced and sensed by all cells, not just nerves and muscles ; in vivo, these activities build bioelectric circuits that direct individual cell behaviors toward specific anatomical goals. Electrospinning is the best candidate for producing novel electroactive textile meshes that mimic extracelullar matrix. New fields of research is needed on electrospun electroactive polymers, biodegredable and nondegredable textiles. There is a demand for this kind of materials to help diseeses like motor neuron disease, Alzheimer's disease, neurological scoliosis, spinal muscular atrophy (SMA), injured/cut spinal cords. Polymers like polypyrrole (PPy), polyaniline (PANI), polythiophene (PT), polyvinylidene fluoride (PVDF), poly(vinylidene fluoride– trifluoroethylene) (P(VDF– TrFE)) and polyurethane display good electrocunductive properties which can be used in further exploring the electrospun electroactive/conductive textiles fields of study [1, 2]. Incorporation of EAP-s with cells brings us closer to achivieng the goal of developing textile composites of organic and non-organic materials that are interweaved and functional together.

medical textiles ; electrospinning ; electroactive polymers ; nerve repair

nije evidentirano