Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1182671

Anticoagulant Treatment in Patients with Atrial Fibrillation and Chronic Kidney Disease


Popović, Marta; Altabas, Karmela; Trbušić, Matias
Anticoagulant Treatment in Patients with Atrial Fibrillation and Chronic Kidney Disease // Acta clinica Croatica, 60 (2021), Supplement 1; 102-113 doi:10.20471/acc.2021.60.s1.15 (recenziran, članak, znanstveni)


CROSBI ID: 1182671 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Anticoagulant Treatment in Patients with Atrial Fibrillation and Chronic Kidney Disease

Autori
Popović, Marta ; Altabas, Karmela ; Trbušić, Matias

Izvornik
Acta clinica Croatica (0353-9466) 60 (2021), Supplement 1; 102-113

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
atrial fibrillation ; anticoagulant treatment ; chronic kidney disease

Sažetak
Aim: To investigate the efficacy and safety profile of oral anticoagulants and determine the best treatment for patients with atrial fibrillation (AF) and chronic kidney disease (CKD). Methods and materials: A systematic assessment of literature from Pubmed/MEDLINE was performed in search of studies evaluating the efficacy, safety, pharmacokinetics, and pharmacodynamics of direct oral anticoagulants (DOACs) and warfarin in patients with CKD. Results: According to guidelines, DOACs are the treatment of choice for patients with CKD 1–3 (Crcl ≥ 30 mL/min) due to their high efficacy, better safety profile, and fewer food/drug and drug/ drug interactions than warfarin. For patients with CKD 4 (Crcl 15-29 mL/min), there are no such strong recommendations as to which group of anticoagulants is the better choice, and for those with CKD 5 (Crcl <15 mL/min), the choice is currently narrowed to warfarin or apixaban. However, there seem to be more negative effects of warfarin, including accelerated CKD progression and increased risk of bleeding compared to DOACs. Conclusion: Considering their superior safety profile and the possibility of apixaban, rivaroxaban, and edoxaban to achieve an adequate anticoagulant effect even in severe kidney disease, DOACs seem to be a better option for anticoagulant treatment of patients with AF and CKD.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Stomatološki fakultet, Zagreb,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Opća bolnica Varaždin

Profili:

Avatar Url Matias Trbušić (autor)

Avatar Url Karmela Altabas (autor)

Poveznice na cjeloviti tekst rada:

doi hrcak.srce.hr

Citiraj ovu publikaciju:

Popović, Marta; Altabas, Karmela; Trbušić, Matias
Anticoagulant Treatment in Patients with Atrial Fibrillation and Chronic Kidney Disease // Acta clinica Croatica, 60 (2021), Supplement 1; 102-113 doi:10.20471/acc.2021.60.s1.15 (recenziran, članak, znanstveni)
Popović, M., Altabas, K. & Trbušić, M. (2021) Anticoagulant Treatment in Patients with Atrial Fibrillation and Chronic Kidney Disease. Acta clinica Croatica, 60 (Supplement 1), 102-113 doi:10.20471/acc.2021.60.s1.15.
@article{article, author = {Popovi\'{c}, Marta and Altabas, Karmela and Trbu\v{s}i\'{c}, Matias}, year = {2021}, pages = {102-113}, DOI = {10.20471/acc.2021.60.s1.15}, keywords = {atrial fibrillation, anticoagulant treatment, chronic kidney disease}, journal = {Acta clinica Croatica}, doi = {10.20471/acc.2021.60.s1.15}, volume = {60}, number = {Supplement 1}, issn = {0353-9466}, title = {Anticoagulant Treatment in Patients with Atrial Fibrillation and Chronic Kidney Disease}, keyword = {atrial fibrillation, anticoagulant treatment, chronic kidney disease} }
@article{article, author = {Popovi\'{c}, Marta and Altabas, Karmela and Trbu\v{s}i\'{c}, Matias}, year = {2021}, pages = {102-113}, DOI = {10.20471/acc.2021.60.s1.15}, keywords = {atrial fibrillation, anticoagulant treatment, chronic kidney disease}, journal = {Acta clinica Croatica}, doi = {10.20471/acc.2021.60.s1.15}, volume = {60}, number = {Supplement 1}, issn = {0353-9466}, title = {Anticoagulant Treatment in Patients with Atrial Fibrillation and Chronic Kidney Disease}, keyword = {atrial fibrillation, anticoagulant treatment, chronic kidney disease} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font