engleski

Therapy of Recurrent Aphthous Stomatitis in Pregnant Patients

Recurrent aphthous stomatitis or recurrent aphthous ulcerations are ulcerative lesions of the oral mucosa of unknown etiology, with varying prevalence. Due to the recurrent nature of these lesions, it is possible that the true prevalence of recurrent aphthous stomatitis is greater than that reported. Keywords: Stomatitis ; Aphthous ; Ulcerations ; Recurrent Aphthous ; Therapy ; Pregnancy, Risk Therapeutic options include treatment with topical or systemic glucocorticoid, immunosuppressant, antimicrobial or anti- inflammatory therapy. During pregnancy, exposure to some drugs may adversely affect the fetus so the objective of this article is to discuss available therapeutic options for recurrent aphthous stomatitis in pregnancy. PubMed database was searched for full-text articles in English language, with key words “recurrent aphthous ulcerations” and “recurrent aphthous stomatitis treatment” and “recurrent aphthous stomatitis in pregnancy”. For some agents, data for topical use in humans are limited so pregnancy recommendations are given only for systemic intake. Pregnancy risk categories have been determined by Food and Drug Administration and they represent differences in the degrees of a fetal risk regarding use of a specific drug during pregnancy. Pregnant patients with RAS should be informed about the risk level of the potential drug for the fetus so that they can actively participate in the decision about the treatment. Topical therapy is the therapy of choice. It is effective in most cases and has well-tolerable side-effects.

stomatitis ; aphthous ; ulcerations ; recurrent aphthous ; therapy ; pregnancy, risk

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