Surgical and seizure treatment outcomes in adult dysembryoplastic neuroepithelial tumors: a case series (CROSBI ID 306368)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Sajko, Tomislav ; Rotim, Krešimir ; Jurilj, Mia ; Rotim, Ante ; Splavski, Bruno ; Jurčić Čulina, Ivana
engleski
Surgical and seizure treatment outcomes in adult dysembryoplastic neuroepithelial tumors: a case series
Dysembryoplastic neuroepithelial tumors (DNETs) are benign neoplasms classified in the category of glioneuronal tumors. The estimated incidence of DNETs is 0.03 per 100, 000 person per year with the age peak in a range between 10 and 14 years, and decreasing dramatically with increasing age. They are seldom diagnosed in persons above 20 years of age, being a cause of tumor-related intractable epilepsy that begins in childhood or adolescence. They have been proven to be the second most common type of epileptogenic tumors in pediatric population. These rare tumors cause chronic drug- resistant partial complex seizures with or without secondary generalization. Herein, we provide institutional case series of six adult patients with temporal lobe DNET presenting with complex partial seizures. Lesionectomy was performed with tumor resection in toto in three patients. In another three, partial resection was performed, whereas tumor remnant was left intact to avoid possible basal ganglia damage. All patients were seizure free postoperatively. Lesionectomy alone in temporal lobe epilepsy was associated with less favorable outcome than anterior temporal lobectomy. Total tumor removal is considered a major prognostic factor in most studies.
dysembryoplastic neuroepithelial tumor ; seizure ; surgery ; outcome
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Podaci o izdanju
60 (4)
2021.
627-630
objavljeno
0353-9466
1333-9451
10.20471/acc.2021.60.04.09
Povezanost rada
Kliničke medicinske znanosti