engleski

BLOOD PRESSURE CONTROL IN VERY OLD HEMODIALYSIS PATIENTS IN DALMATIA COUNTY (SOUTHERN CROATIA)

Introduction and Aims: Poor blood pressure control in very old patients with end stage renal disease (ESRD) on maintenance haemodialysis (HD) is the cause of cerebrovascular and cardiovascular morbidity and mortality. The aim of this study was to revealed blood pressure control among very old HD patients. Methods: We investigated 402 patients (170 and 232 males) mean age 68.13±13.8 years on maintenance HD 4.73±5.17 years. Out of all HD patients, 81 patients (20.1%) were >80 years of age. For every study subjects pre HD, after 2 hours (2 hrs HD) and post HD recumbent systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured during middle week HD session. Results: Differences in blood pressure parameters between subjects >80 years of age (N= 81) and subjects <= 80 years of age (N=321) are shown in Table 1. Statistically significant correlation between age and pre HD DBP, pre HD MAP, post HD DBP and post HD MAP was found (r=-0.248 ; p=0.000), (r=-0.179 ; p=0.000), (r=-0.168 ; p= <0.001), (r=-0.121 ; p=0.008) respectively. Also, significant correlation between age and 2 hrs HD SBP, 2 hrs HD DBP and 2 hrs HD MAP was found (r=-0.091 ; p=0.034), (r=-0.201 ; p=0.000), (r=-0.159 ; p=0.001) respectively. Conclusions: The results from this multicentre study have shown statistically lower blood pressure in very old HD patients. In this population of HD patients hypotension also might be risk of cerebrovascular and cardiovascular morbidity and mortality. Further studies need to be conducted to determine best HD treatment and combination of antihypertensive medications and optimal dosing in order to improve BP control and prevent hypotension in this population of HD patients.

blood pressure, hemodialysis

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