Successful treatment with Cinryze® replacement therapy of a pregnant patient with hereditary angioedema: a case report (CROSBI ID 305902)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Kardum, Željka ; Prus, Višnja ; Milas Ahić, Jasminka ; Kardum, Darjan
engleski
Successful treatment with Cinryze® replacement therapy of a pregnant patient with hereditary angioedema: a case report
Background: Hereditary angioedema (HAE) is a rare disease characterized with recurrent swelling of subcutaneous or mucosal tissue that resolves in approximately 3 days. It can be presented with peripheral edema, abdominal and life-threatening laryngeal angioedema. A variety of triggers are known to cause episodes of angioedema including estrogen exposure. There are diferent reports regarding the efect of pregnancy on HAE attacks, and in some patients, the pregnancy is a recognized triggering factor. Case presentation: We present a female Caucasian patient with pre-existing HAE and disease exacerbations during pregnancy, requiring prophylactic use of plasma-derived C1 inhibitor concentrate. She was treated with Cinryze® replacement therapy throughout the pregnancy 1000 IU i.v. 48 times. She gave birth to a healthy male infant, via C-section. After the delivery, the patient was symptom-free for 6 months and required no treatment for HAE. Conclusions: In the case presented, the angioedema attacks worsened as the pregnancy progressed. The treatment with Cinryze® replacement therapy was efective and safe during pregnancy, with no adverse efects on the infant.
Hereditary angioedema ; Pregnancy ; C1 replacement therapy ; Cinryze® ; Case report
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o izdanju
Povezanost rada
Kliničke medicinske znanosti