engleski

Control of calcium phosphate crystal nucleation, growth and morphology by polyelectrolytes

Crystal growth of calcium hydrogenphosphate dihydrate (DCPD), in the presence of polyaspartic acid or calcium phytate (system A), as well as nucleation and growth of octacalcium phosphate (OCP), in the presence of poly-l-lysine, poly-l- glutamic acid or polystyrene sulfonate (system B) have been investigated. In system A crystallization of DCPD was inhibited and the crystal growth morphology was specifically modified by preferential interaction of the respective additive with the dominant (010) crystal face. In system B crystals were formed via precursor phase(s) and polyelectrolytes exhibited dual action, at low concentrations inducing and at high concentrations inhibiting nucleation of the crystalline phase. Crystal/additive interactions controlling growth were nonspecific and resulted in smaller crystals with rounded edges, but with the same basic orientation as in the controls.

precipitation, phase transformation, crystal growth morphology, calcium hydrogenphosphate dihydrate, amorphous calcium phosphate, octacalcium phosphate, polyaspartic acid, calcium phytate, poly-l-lysine, poly-l-glutamic acid, polystyrene sulfonate

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