engleski

The association between dry eye disease and use of psychiatric medications

Dry eye disease (DED) is one of the most common ocular morbidities, and often results in significant eye discomfort, visual disturbances and potential damage to the corneal surface. Dry eye syndrome is a very common eye condition that affects quality of life as an important and common public health problem. Dry eye can be caused by different mechanisms. Many systemic medications have been associated with ocular and visual side effects that require patient management. Some medications used in psychiatry are known to cause ocular drying. Studies showed that these medications also contribute to decrease of tear film production. Ocular dryness is well-recognized adverse side effect of many topical and systemic medications. In psychiatry, patients with depression, schizophrenia and other psychotic disorders, PTSD or bipolar disorders, who have consumed such drugs as antidepressants, antipsychotics, lithium carbonate and sodium valproate frequently experience dry eye symptoms. Many ophthalmologic effects of psychiatry medications can only be identified with a complete examination and since the eye is an organ system frequently ignored by therapists, these effects are considered in frequently. It seems likely that incidence of ocular side effects increases sharply with the use of polypharmacy that is very common in psychiatric patients. Psychiatrists and ophthalmologists need to be aware of and prepared for any associated medication-induced adverse effect such as dry eye. Clinicians should try to use the lowest dose possible to achieve the desired therapeutic effect. In treatment of psychiatric patients only integrative and transdisciplinary approach will results with better functioning and higher quality of life.

dry eye disease ; psychiatric medications ; polypharmacy ; treatment

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