Comparison of the Schein and OSDI questionnaire as indicator of tear film stability in patients with schizophrenia (CROSBI ID 714111)
Prilog sa skupa u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Bakija, Ivana ; Filipčić, Igor ; Bogadi, Marija ; Šimunović Filipčić, Ivona ; Gotovac, Marta ; Kaštelan, Snježana
engleski
Comparison of the Schein and OSDI questionnaire as indicator of tear film stability in patients with schizophrenia
Background: The aim of this research was to determine which of two chosen questionnaires for subjective symptoms of dry eye (Ocular Surface Disease Index and Schein questionnaire) is more reliable in the assessment of dry eye in patients with schizophrenia. Subjects and methods: Our research included 80 patients (160 eyes) of both sexes with schizophrenia ranging between the age of 25 and 55 who have been taking one of three antipsychotic drugs namely clozapin, olanzapin, quetiapin for five or more years and were in a stable phase of the disease or remission. All participants were required to satisfy all included and excluded criteria. They all filled out the Schein and OSDI questionnaires for assessment of subjective symptoms. Tear break-up time test (TBUT) for objective evaluation of tear film stability was also performed. In order to determine the correlation between two subjective and objective tests we calculated Spearmans correlation coefficients. Results: Obtained results of the correlation between OSDI questionnaire and TBUT test for the right eye was r=-0.73 ; p<0.01 and for the left eye was r=-0.72 ; p<0.01. Results of the correlation between Schein questionnaire and TBUT test for the right eye was r=-0.62 ; p<0.01 and for the left eye was r=-0.60 ; p<0.01. A detailed analysis shows that there are no statistically significant differences between the correlations. Both subjective questionnaires are statistically significantly and negatively related to the TBUT test, showing that an increase in the results on the OSDI and Schein's questionnaires led to the decreases in the results on the TBUT test. Conclusion: In patients with schizophrenia the OSDI and Schein questionnaires are equally reliable in the assessment of subjective symptoms of Dry eye disease. Considering that, OSDI is more common in clinical practice and includes questions regarding quality of life, it would have certain advantages and it is recommended for use in patients with schizophrenia.
Shein questionnaire ; OSDI questionnaire ; tear film stability ; schizophrenia
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Podaci o prilogu
596-603.
2021.
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objavljeno
Podaci o matičnoj publikaciji
Psychiatria Danubina
0353-5053
1849-0867
Podaci o skupu
29th Danubian psychiatric symposium and IX Croatian congress on psychopharmacotherapy
poster
18.03.2021-20.03.2021
online ; Zagreb, Hrvatska
Povezanost rada
Kliničke medicinske znanosti