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Photokilling Squamous Carcinoma Cells SCCVII with Ultrafine Particles of Selected Metal Oxydes (CROSBI ID 100477)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Ivanković, Siniša ; Gotić, Marijan ; Jurin, Mislav ; Musić, Svetozar Photokilling Squamous Carcinoma Cells SCCVII with Ultrafine Particles of Selected Metal Oxydes // Journal of sol-gel science and technology, 27 (2003), 225-233. doi: 10.1023/A:1023715004575

Podaci o odgovornosti

Ivanković, Siniša ; Gotić, Marijan ; Jurin, Mislav ; Musić, Svetozar

engleski

Photokilling Squamous Carcinoma Cells SCCVII with Ultrafine Particles of Selected Metal Oxydes

The ability of ultrafine particles of TiO2, WO3 and iron-doped TiO2 to kill cancer cells in the presence of UV irradiation was investigated. The best photokilling effect on carcinoma cells SCVII cultured in vitro showed iron-doped TiO2 ultrafine particles synthetized by the sol-gel procedure with starting chemicals Ti(IV)-isopropoxide and anhydrous Fe(II)-acetate. It was found that a small particle size and high dispersity influenced citotoxicity and photokilling efficiency. The remarcable photokilling effect of highly iron-doped TiO2 ultrafine particles (the molar ratio Fe/Ti=0.136) in the presence of UV irradiation was observed. The influence of ultrafine metal oxide particles on the inhibition of cancer cell prolifeartion was measured using 3H-thymidine incorporation test. The possible mechanisms involved in the photokilling of carcinoma cells with ultrafine particles of selected metal oxydes was discussed.

TiO2 ; WO3 ; iron-doped TiO2 ; ultrafine particles ; cancer cells ; photokilling effect

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Podaci o izdanju

27

2003.

225-233

objavljeno

0928-0707

10.1023/A:1023715004575

Povezanost rada

Kemija

Poveznice
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