Novel yeast extract is superior to colloidal oatmeal in providing rapid itch relief (CROSBI ID 303871)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Dhurat Rachita ; Sharma Aseem ; Surve Ravina ; McCoy John ; Kovacevic Maja ; Goren Andy ; Tan Yimei ; Zou Ying ; Goldust Mohamad, Šitum Mirna ; Stanimirovic Andrija
engleski
Novel yeast extract is superior to colloidal oatmeal in providing rapid itch relief
Background: Approximately, 13.5% of the population suffers from chronic itch. Many cosmetic and pharmaceutical treatments for itch are available ; however, cosmetic treatments are not reliably effective and most pharmaceutical formulations carry the risk of adverse events with chronic use. Aims: Previously, we have reported a novel extraction process of Saccharomyces cerevisiae, that is, Baker's yeast. The extract obtained from the novel process demonstrates superior anti-itch properties compared to other yeast extracts. In our previous study, we demonstrated that, after 30 minutes, the extract significantly reduced itch when compared to a placebo lotion (P = .002). Methods: In the present study we conducted a head- to-head comparison with the leading cosmetic itch product: lotion containing colloidal oatmeal (CO). A randomized double-blinded study of 60 patients was conducted. Results: In our study, the novel yeast extract was vastly superior to the CO containing lotion (Aveeno™ Eczema Therapy Moisturizing Cream). We saw statistically significant difference in the reduction of itch (P = .0001) using the novel yeast extract vs the CO lotion. Additionally, the yeast extract was shown to relieve itch in as little as one minute after application. Conclusion: The novel yeast extract rapidly relieves itch and is superior to the cosmetic market leader, CO lotion.
chronic effect ; cosmetic ; pruritis
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Podaci o izdanju
20 (1)
2021.
207-209
objavljeno
1473-2130
1473-2165
10.1111/jocd.13436
Povezanost rada
Kliničke medicinske znanosti