engleski

Marine-derived polysaccharides from Adriatic Sea: Investigation of diverse biological activities

Among a large number of marine extracts and different isolated bioactive compounds, polysaccharides are recognized as one of the most promising sources of different biological activity (Shi et al, 2017 ; Gopu & Selvam, 2020). This is highly influenced by their growth location and harvesting season that cause even intraspecies variation, thus offering an inexhaustible source of novel bioactive compounds (Jiao et al., 2011) with unique physiological and chemical properties, including anti-inflammatory, antioxidant, antimicrobial, antiviral, anti-coagulant, and antitumor activities (Lee et al, 2017). Nevertheless, marine-derived polysaccharides are still under-exploited, thus paving the way for a new trend in the discovery of compounds from a sustainable source. This study aimed to conduct comprehensive research and determine biological activities (antioxidant, antibacterial, and antifungal) of water-soluble polysaccharide extracts from 10 marine species from the Croatian coast of the Adriatic Sea: 2 green algae (Ulva lactuca and Codium bursa), 5 brown algae (Fucus virsoides, Padina pavonica, Cystoseira barbata, Halopteris scoparia, and Cystoseira compressa), 1 coral (Eunicella cavolini), 1 sea squirt (Aplidium conicum) and 1 sponge (Chondrosia reniformis), along with embryotoxicity and mutagenic potential to determine their safety for non-target organisms and humans.

Macroalgae ; polysaccharides ; bioactivity

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