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THE POTENTIAL OF Cannabis sp. IN PAIN MEDICINE: A PERSPECTIVE

Long before they were even properly named, plants form Cannabis genus (C. indica L., C. sativa L. and C. ruderalis L.) had their usefulness in the folk medicine. Recently, it has been scientifically proven that cannabinoids mainly act through two types of endocannabinoid receptors in the central nervous system (CB1) and immune cells (CB2). The usage can be either from recreational usage in glaucoma or in research for acute and chronic pain therapy. Some clinical studies support the use of hemp oil and hemp seed in the pain medicine. However, until today, there is still no evidence to suggest that medical cannabis can be used solely as cure, but the use of hemp seed and oil from hemp seeds or flowers in practice, refers to symptomatic treatment as adjunctive therapy. Treatment consists of an individual dose titration phase (with patient supervision) of delta-9-tetrahidrocannabinol (THC) or cannabidiol (CBD) and a maintenance phase. The main goal of this is study was the overview of therapeutic benefit to the familiar and wildly used hemp plant in acute and chronic pain, mostly because of its cost-effectiveness. Overall, this review paper highlights more possibilities of hemp plant usage in further symptomatic pain treatments.

hemp oil, hemp seed, acute pain, chronic pain, humans, THC, CBD

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