engleski

Intima-media thickness and coronary artery bypass grafting surgery

Objective: The aim of this study was to evaluate the relationship between common carotid artery intima-media thickness and risk factors in patients who underwent coronary artery bypass grafting surgery (CABG) based on extent of coronary artery disease. Material and Methods: This study included all patients with coronary artery disease hospitalized in the Department of Cardiology during the period from 2007 to 2014, who underwent CABG. Two groups were formed: patients who underwent CABG of three and more vessels (CABG 3+) and patients who underwent CABG of two or less vessels (CABG 2-). Carotid intima-media thickness (C-IMT) was assessed by carotid ultrasound according to the Mannheim Carotid Intima-Media Thickness Consensus. Results: The study included 66 patients. There were 35 patients in the CABG3+ group and 31 patients in the CABG2- group. We found no statistically significant difference in the mean intima-media thickness of the common carotid artery between these two groups (p= 0.5637), neither between C-IMT and the extent of the coronary artery disease (p=0.82612). The CABG 3+ group had higher incidence of arterial hypertension (p=0.0298) and hyperlipidemia (p=0.0388). No statistically significant difference was found between age, gender, previous ischemic stroke, and smoking between groups. Discussion: Our study did not show statistically significant relationship between common carotid artery (CCA) IMT and the extent of CABG surgery and coronary artery disease. Arterial hypertension and hyperlipidemia are more important risk factors, more commonly present in patients with greater extent of CABG surgery.

atherosclerosis, coronary artery bypass grafting, coronary artery disease, coronary artery surgery, intima media complex

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