engleski

Preliminary histological analysis of two biomaterials after socket preservation

Following tooth extraction, the alveolar ridge undergoes dimensional changes. Various biomaterials are used to reduce alveolar ridge volume loss following tooth extraction by stimulating new bone formation. Maxresorb® inject (Botiss Biomaterials GmbH, Germany) is a biphasic material composed of a water-based gel with 60% hydroxyapatite and 40% β-tricalcium phosphate. BioOss® (Geistlich Pharma AG, Switzerland) is a porous bone mineral matrix which is produced by removing all organic components from bovine bone. This study aimed to examine the regenerative potential of biphasic calcium phosphate (BCP) (Maxresorb® inject), by assessing histological results of bone biopsy and comparing them to inorganic bovine bone (BioOss®), after a healing period of 6 months. In the first phase, 36 patients were divided randomly into 2 groups of 18 individuals. The first group underwent tooth extractions and socket augmentation with Maxresorb® inject. In the other group socket preservation was performed using BioOss®. In both groups, the sockets were covered by native collagen membrane. Atfer 6 months of healing, biopsy was harvested prior to implant placement for histological analysis. The preliminary histological analysis revealed remaining BCP particles in intimate contact with the newly formed bone in the case of Maxresorb® inject. Histological specimens of BioOss® also showed incorporation of the hydroxyapatite particles into the newly mineralized bone. In both materials, there were no histological signs of tissue inflammation. Furthermore, both materials exhibited easy handling and patients had no complications during healing period. Although a small number of patients were treated, along with the preliminary nature of study, histological findings indicate osteoconductive properties of both materials included in this study. However, additional research is required to obtain histological and clinical features of Maxresorb® inject and BioOss® regarding their osteocondutive properties.

dental implantology ; augmentation ; alloplast ; xenograft ; histomorfometry

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