Pregled bibliografske jedinice broj: 1162858
Enantioselective construction of a tetrasubstituted stereocenter in isoindolinones via an organocatalyzed reaction between ketones and 3-hydroxyisoindolinones
Enantioselective construction of a tetrasubstituted stereocenter in isoindolinones via an organocatalyzed reaction between ketones and 3-hydroxyisoindolinones // Chemical communications, 57 (2021), 13546-13549 doi:10.1039/d1cc05761h (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1162858 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Enantioselective construction of a
tetrasubstituted stereocenter in isoindolinones
via an organocatalyzed reaction between ketones
and 3-hydroxyisoindolinones
Autori
Matišić, Mateja ; Gredičak, Matija
Izvornik
Chemical communications (1359-7345) 57
(2021);
13546-13549
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Enantioselective synthesis ; Organocatalysis ; Isoindolinones ; Ketones
Sažetak
An efficient enantioselective reaction between ketones and 3-hydroxyisoindolinones is described. In a reaction catalyzed by a chiral phosphoric acid, a broad range of ketones and in situ generated ketimines afforded isoindolinone derivatives comprising a tetrasubstituted stereocenter in high yields and enantioselectivities. The developed methodology is also suitable for the construction of compounds with vicinal stereogenic centers.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
HRZZ-IP-2018-01-4053 - Nove strategije za pripravu tetrasupstituiranih kiralnih centara: asimetrične katalitičke reakcije usmjerene protuanionom (NSYNC-ACDC) (Gredičak, Matija, HRZZ - 2018-01) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
- Nature Index
