engleski

Polyelectrolyte multilayers: From fundamental studies to biomedical applications

Polyelectrolyte multilayers (PEMs) are surface coatings created by alternating deposition of positively and negatively charged polyelectrolytes (polycations and polyanions) on a solid surface. PEM build-up strongly depends on applied experimental conditions (e.g. ionic strength, supporting electrolyte type, pH and concentration). The goal of our research was finding the answers to fundamental questions concerning the PEM build-up. [1] We examined the influence of various experimental conditions on PEM formation and compared the PEM properties with the properties of corresponding polyelectrolyte complexes in solution. [2] Furthermore, the possibility of PEM biomedical application was explored, with the emphasis on prevention of bacterial adhesion to various surfaces. [3-5] In recent years we have developed new successful strategies for designing soft nano materials whose properties can be finely adjusted according to application requirements.

Polyelectrolytes, Polyelectrolyte multilayers, Biomedical applications

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