engleski

Evaluation of gut microbial enzyme activity after consummation of laurel and myrtle extract in rat

Polyphenols exhibit structural diversity, which impacts on bioavailability, metabolism, and bioactivity. The gut microbiota play a key role in modulating the production, bioavailbility and, thus the biological activities of phenolic metabolites, particularly after intake of food containing high-molecular-weight polyphenols. The main aim of this study was to investigate whether polyphenols alter intestinal microbiota and their enzymatic activity after intake of Laurel and Myrtle water extract and whether changes in intestinal enzyme activity affect the health of rats. We investigated growth of lactic acid bacteria (LAB), β-glucuronidase, β-glucosidase, β galactosidase activity, pH value, body weight change and food effecacy ration after intragastric treatment of rats with Laurel and Myrtle extract at doses of 50 and 100 mg/kg during two weeks. The endogenous populations of colonic probiotic bacteria (Lactobacilli and Bifidobacteria) were counted on selective media. According to our data Laurel in the applied dose of 50 and 100 and Myrtle (100 mg/kg) positively affect the health of rats by increasing the number of colonies of Lactobacilli and Bifidobactera compared to the control group, causes minor changes in enzyme activity, and in high doses Laurel increases food efficiency ratio, while Myrtle in a reduced dose.

laurel and myrtle extract ; gut microbial enzymes ; probiotic bacteria

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