engleski

ANTICOAGULANT THERAPY IN SECONDARY STROKE PREVENTION

Atrial fibrillation is well known risk factor for ischemic stroke. The oral anticoagulant therapy with vitamin K antagonists have been a gold standard for secondary prevention of cardioembolic stroke. Development and presence of direct oral anticoagulants (direct thrombin inhibitors and direct inhibitors of factor Xa) with at least similar efficacy and better safety profile included them into guidelines. Aspirin is the gold standard of prevention of noncardioembolic stroke, but it seems lost the role in primary stroke prevention, as well as in patients with non-valvular atrial fibrillation. The current dilemmas regarding usage of oral anticoagulant therapy will be discussed.

stroke prevention

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