engleski

Intraoperative parathyroid hormon measurements in femal with parathyroid adenoma

Primary hyperparathyroidism (PHPT) is disorder characterized by increased and uncontrolled parathyroid hormone secretion, cause of hyperfunction of one or more parathyroid glands. In 80-85% cases of PHPT is caused by parathyroid adenoma. Persistent hyperparathyroidism leads to altered osseous metabolism involving bone resorption and tissue changes. In rare cases, approximately in every thirteenth patient with PHPT, the bone mass is suspected of being a neoplastic lesion - brown tumor induced by primary hyperparathyroidism. The only way of PHPT correction is surgical elimination hyperactive parathyroid glands. In this article we report the first case of intraoperative parathyroid hormone measurements for primary hyperparathyroidism in Republic of Croatia. The possibility of intraoperative PTH monitoring provides an additional patient and operator safety. Intraoperative PTH becomes an exact instructor (navigator) to operator –surgeon. On the basis of decreasing value of this peptide with very short half-life time, surgeon makes immediate decision if the operation is completed or he requires further excision parathyroid glands because of hyperplasia. Guarantee of successful diagnosis, which is a prerequisite for the correct treatment, is a multidisciplinary, continuous, systematic and synchronized cooperation of whole and heterogeneous medical team, which includes clinicians, radiologists, cytologists, pathologists and medical biochemists.

Intraoperative PTH, parathyroid adenoma

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