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Pregled bibliografske jedinice broj: 1155783

Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge


Pešut, Ena; Đukić, Anamaria; Lulić, Lucija; Skelin, Josipa; Šimić, Ivana; Gašperov, Nina Milutin; Tomaić, Vjekoslav; Sabol, Ivan; Grce, Magdalena
Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge // Viruses-Basel, 13 (2021), 11; 2234, 32 doi:10.3390/v13112234 (međunarodna recenzija, pregledni rad, znanstveni)


CROSBI ID: 1155783 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge

Autori
Pešut, Ena ; Đukić, Anamaria ; Lulić, Lucija ; Skelin, Josipa ; Šimić, Ivana ; Gašperov, Nina Milutin ; Tomaić, Vjekoslav ; Sabol, Ivan ; Grce, Magdalena

Izvornik
Viruses-Basel (1999-4915) 13 (2021), 11; 2234, 32

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
human papillomaviruses (HPV) ; oncoproteins ; proteomics ; epigenetics ; biomarkers ; cancer ; therapeutics ; immunology

Sažetak
Human papillomaviruses (HPVs), which are small, double-stranded, circular DNA viruses infecting human epithelial cells, are associated with various benign and malignant lesions of mucosa and skin. Intensive research on the oncogenic potential of HPVs started in the 1970s and spread across Europe, including Croatia, and worldwide. Nowadays, the causative role of a subset of oncogenic or high-risk (HR) HPV types, led by HPV- 16 and HPV-18, of different anogenital and head and neck cancers is well accepted. Two major viral oncoproteins, E6 and E7, are directly involved in the development of HPV-related malignancies by targeting synergistically various cellular pathways involved in the regulation of cell cycle control, apoptosis, and cell polarity control networks as well as host immune response. This review is aimed at describing the key elements in HPV-related carcinogenesis and the advances in cancer prevention with reference to past and ongoing research in Croatia

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
HRZZ-IP-2019-04-3403 - Multifaktorna analiza HPV inficiranih stanica u nastanku raka vrata maternice (MACCD) (Sabol, Ivan, HRZZ - 2019-04) ( POIROT)
HRZZ-IP-2016-06-2246 - Rasvjetljivanje onkogenih funkcija E6/E7 HPV-a na različitim anatomskim mjestima (HPVHNC) (Tomaić, Vjekoslav, HRZZ - 2016-06) ( POIROT)
IP-2013-11-4758 - Epigenetičke promjene karcinoma pločastih stanica glave i vrata (EpiC-HNSCC) (Grce, Magdalena, HRZZ - 2013-11) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com fulir.irb.hr doi.org

Citiraj ovu publikaciju:

Pešut, Ena; Đukić, Anamaria; Lulić, Lucija; Skelin, Josipa; Šimić, Ivana; Gašperov, Nina Milutin; Tomaić, Vjekoslav; Sabol, Ivan; Grce, Magdalena
Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge // Viruses-Basel, 13 (2021), 11; 2234, 32 doi:10.3390/v13112234 (međunarodna recenzija, pregledni rad, znanstveni)
Pešut, E., Đukić, A., Lulić, L., Skelin, J., Šimić, I., Gašperov, N., Tomaić, V., Sabol, I. & Grce, M. (2021) Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge. Viruses-Basel, 13 (11), 2234, 32 doi:10.3390/v13112234.
@article{article, year = {2021}, pages = {32}, DOI = {10.3390/v13112234}, chapter = {2234}, keywords = {human papillomaviruses (HPV), oncoproteins, proteomics, epigenetics, biomarkers, cancer, therapeutics, immunology}, journal = {Viruses-Basel}, doi = {10.3390/v13112234}, volume = {13}, number = {11}, issn = {1999-4915}, title = {Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge}, keyword = {human papillomaviruses (HPV), oncoproteins, proteomics, epigenetics, biomarkers, cancer, therapeutics, immunology}, chapternumber = {2234} }
@article{article, year = {2021}, pages = {32}, DOI = {10.3390/v13112234}, chapter = {2234}, keywords = {human papillomaviruses (HPV), oncoproteins, proteomics, epigenetics, biomarkers, cancer, therapeutics, immunology}, journal = {Viruses-Basel}, doi = {10.3390/v13112234}, volume = {13}, number = {11}, issn = {1999-4915}, title = {Human Papillomaviruses-Associated Cancers: An Update of Current Knowledge}, keyword = {human papillomaviruses (HPV), oncoproteins, proteomics, epigenetics, biomarkers, cancer, therapeutics, immunology}, chapternumber = {2234} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





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